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David Pleasure Selected Research

Gliosis

10/2013Origins and significance of astrogliosis in the multiple sclerosis model, MOG peptide EAE.
1/2008Bone morphogenetic proteins 4, 6, and 7 are up-regulated in mouse spinal cord during experimental autoimmune encephalomyelitis.

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David Pleasure Research Topics

Disease

10Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental)
12/2021 - 01/2007
9Multiple Sclerosis
01/2022 - 01/2007
8Demyelinating Diseases (Demyelinating Disease)
01/2017 - 08/2007
7Canavan Disease (Leukodystrophy, Spongiform)
01/2024 - 05/2015
3Atrophy
12/2023 - 11/2017
3Ataxia (Dyssynergia)
12/2023 - 01/2020
3Central Nervous System Diseases (CNS Diseases)
01/2012 - 10/2002
3Ischemia
08/2008 - 10/2002
2Charcot-Marie-Tooth Disease (Peroneal Muscular Atrophy)
01/2016 - 03/2005
2Gliosis
10/2013 - 01/2008
2Hypoxia (Hypoxemia)
08/2011 - 02/2002
2Brain Ischemia (Cerebral Ischemia)
05/2008 - 10/2002
2Inflammation (Inflammations)
01/2008 - 01/2007
2Necrosis
03/2003 - 10/2002
1Disease Progression
12/2021
1Paralysis (Palsy)
01/2012
1Relapsing-Remitting Multiple Sclerosis
11/2011
1Neuromuscular Diseases (Neuromuscular Disease)
04/2011
1Microcephaly
12/2010
1Neuroblastoma
04/2010
1Mitochondrial Diseases (Mitochondrial Disease)
03/2010
1Pain (Aches)
08/2008
1Partial Epilepsies (Epilepsy, Partial)
05/2008
1Neurologic Manifestations (Neurological Manifestations)
05/2008
1Infarction (Infarctions)
05/2008
1Olivopontocerebellar Atrophies (Olivopontocerebellar Atrophy)
05/2008
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
05/2008
1Brain Diseases (Brain Disorder)
05/2008
1Encephalitis (Encephalitis, Rasmussen)
05/2008
1Transient Ischemic Attack
05/2008
1Fabry Disease (Fabry's Disease)
03/2005
1Spinal Muscular Atrophy (Progressive Muscular Atrophy)
03/2005
1Inborn Genetic Diseases (Disease, Hereditary)
03/2005
1Fasciculation (Fasciculations)
10/2003
1Wallerian Degeneration
10/2003
1Crush Injuries
10/2003
1Acidosis
03/2003
1Teratocarcinoma
02/2002

Drug/Important Bio-Agent (IBA)

9Peptides (Polypeptides)IBA
06/2014 - 01/2007
9Myelin-Oligodendrocyte GlycoproteinIBA
06/2014 - 01/2007
7aspartoacylaseIBA
01/2024 - 05/2015
5N-acetylaspartate (N-acetyl aspartate)IBA
01/2024 - 05/2015
4EnzymesIBA
12/2023 - 03/2005
3Proteins (Proteins, Gene)FDA Link
01/2012 - 03/2005
3Glutamate Receptors (Glutamate Receptor)IBA
01/2012 - 10/2002
2Antisense OligonucleotidesIBA
12/2023 - 01/2020
2AcetyltransferasesIBA
12/2023 - 01/2018
2Interferon-gamma (Interferon, gamma)IBA
01/2012 - 11/2011
2NestinIBA
08/2011 - 12/2010
2Glial Fibrillary Acidic ProteinIBA
08/2011 - 01/2007
2Messenger RNA (mRNA)IBA
08/2011 - 10/2003
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
08/2011 - 10/2003
2AcidsIBA
08/2008 - 10/2002
2Oxygen (Dioxygen)IBA
03/2003 - 02/2002
2Glucose (Dextrose)FDA LinkGeneric
03/2003 - 02/2002
1CalciumIBA
12/2023
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
01/2022
1myelin oligodendrocyte glycoprotein (35-55)IBA
12/2021
1SodiumIBA
11/2021
1Dicarboxylic Acid TransportersIBA
11/2021
1locked nucleic acidIBA
01/2020
1RNA (Ribonucleic Acid)IBA
01/2018
1ChemokinesIBA
06/2014
1peptide AIBA
06/2014
1CuprizoneIBA
09/2012
1Lysophosphatidylcholines (Lysophosphatidylcholine)IBA
08/2012
1N-Methylaspartate (NMDA)IBA
01/2012
1N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
01/2012
1Interferon-betaIBA
11/2011
1Proteoglycans (Proteoglycan)IBA
11/2011
1VimentinIBA
08/2011
1NucleotidesIBA
04/2011
1InterferonsIBA
01/2011
1Cyclic AMP (AMP, Cyclic)IBA
04/2010
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
04/2010
1Conditioned Culture MediaIBA
04/2010
1Mitochondrial DNA (mtDNA)IBA
03/2010
1Acid Sensing Ion ChannelsIBA
08/2008
1AutoantibodiesIBA
05/2008
1Biomarkers (Surrogate Marker)IBA
05/2008
1Bone Morphogenetic Proteins (Bone Morphogenetic Protein)IBA
01/2008
1Myelin ProteinsIBA
01/2008
1AMPA Receptors (AMPA Receptor)IBA
08/2007
1Fatty Acid-Binding Protein 7IBA
01/2007
1alpha-Galactosidase (Beano)IBA
03/2005
1Ascorbic Acid (Vitamin C)FDA LinkGeneric
03/2005
1NeuropilinsIBA
10/2003
1Semaphorin-3AIBA
10/2003
1LigandsIBA
10/2003
1Kainic Acid (Kainate)IBA
10/2002
1alpha- Amino- 3- hydroxy- 5- methyl- 4- isoxazolepropionic Acid (AMPA)IBA
10/2002
1NF-kappa B (NF-kB)IBA
10/2002
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
10/2002
1Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA
10/2002
1Free RadicalsIBA
02/2002
1Dizocilpine Maleate (Dizocilpine)IBA
02/2002
1FlavonoidsIBA
02/2002

Therapy/Procedure

5Therapeutics
12/2023 - 03/2005
1Cell Transplantation
01/2017
1Precision Medicine
01/2016